BIOTRONIK Home Monitoring Proven to Reduce Risk of All-Cause Mortality for All Types of ICD Patients

Pooled Analysis of Three Clinical Trials Finds 38 Percent Reduced Risk of All-Cause Mortality in ICD Patients Using BIOTRONIK Home Monitoring, by Slowing Heart Failure’s Progression

BERLIN, Germany and ROME, Italy, August 30, 2016 — During a scientific talk at the 2016 European Society of Cardiology (ESC) Congress, Dr. Gerhard Hindricks, Leipzig Heart Center, Germany, presented results of a meta-study showing that BIOTRONIK Home Monitoring® is associated with a 38 percent reduced risk for all-cause mortality after one year in all ICD patients. These results were observed in comparison with conventional office follow-up alone and also found a 36 percent reduction in the combined risk of all-cause mortality or hospitalization for worsening heart failure.

The TRUECOIN study pools 2,405 patients from the TRUST1, ECOST2 and IN-TIME3 trials. The IN-TIME study alone had already shown a more than 50 percent risk reduction for all-cause mortality in heart failure patients specifically. The meta-analysis now extends the mortality benefit to the full range of ICD patients. “It must be pointed out that the clinical benefits have only been demonstrated for BIOTRONIK Home Monitoring. Other studies examining remote monitoring systems could not show this effect,” said lead investigator Dr. Hindricks.

Features Unique to BIOTRONIK Home Monitoring Make the Difference

The pooled study also suggests a link between using BIOTRONIK Home Monitoring specifically and the demonstrated clinical benefits. “The results suggest BIOTRONIK Home Monitoring is effective in helping to reduce mortality in patients with a wide variety of ICD indications, and to slow the progression of heart failure,” commented Dr. Hindricks. “We observed these benefits by analysing studies that only used Home Monitoring, rather than combining data from patients followed using systems that have differing operational features. Hence, analyzing individual remote monitoring systems may be preferable to global analyses.”

BIOTRONIK Home Monitoring is the only remote monitoring system on the market that uses daily transmission verification. “The meta-analysis clearly shows that it does matter which remote monitoring system is used. The daily transmissions, along with multi-parameter analysis and an established clinical workflow, provide physicians with the most robust set of information possible,” stated Manuel Ortega, Senior Vice President, BIOTRONIK. “That wealth of information helps enable intervention earlier, making an appreciable difference in patient care, which this data now confirms.”

1 Varma N, et al. Eur Heart J. 2014, 35 (20).
2 Guedon-Moreau L, et al. Europace. 2014, 16(8).
3 Hindricks G, et al. Lancet. 2014, 384 (9943).

    About BIOTRONIK:

    At BIOTRONIK, patient well-being is our top priority and has been for 60 years. BIOTRONIK is a leading global medical technology company with products and services that save and improve the lives of millions suffering from heart and blood vessel diseases as well as chronic pain. Driven by a purpose to perfectly match technology with the human body, we are dedicated innovators who develop trusted cardiovascular, endovascular and neuromodulation solutions. BIOTRONIK is headquartered in Berlin, Germany, and is represented in over 100 countries.